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Outline
of the company
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Name
Japan SLC, Inc.
* Address: Japan SLC, Inc., 3371-8 Kotoh-cho, Hamamatsu, Shizuoka Prefecture 431-1103
* Tel: +81-53-486-3178 / Fax: +81-53-486-3156
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History
1949: Establishment of Takagi Jikken Dobutsu
Shiikujyo.
1967: Company was reorganized and renamed
as Shizuoka Institute for Laboratory Animals,
Inc.
1987: Company was renamed as Japan SLC,
Inc.
1989: Sales and Delivery Division of Shizuoka
Prefecture Agricultural Cooperative
Association for Animals was transferred
to Japan SLC, Inc.
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Capital stock
95.04 million (JPY)
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Location
Headquarters-Hamamatsu, Shizuoka Prefecture.
Ohara branch-Hamamatsu, Shizuoka Prefecture.
Inasa branch- Inasa-gun, Shizuoka Prefecture.
Haruno branch-Syuchi-gun, Shizuoka Prefecture.
Nakaizu branch- Tagata-gun, Shizuoka Prefecture.
Contract Research Department and Quality
Control Department
-Hamamatsu,
Shizuoka Prefecture.
Tokyo Delivery Center: Machida, Tokyo.
Kyoto Delivery Center: Minami-ku, Kyoto.
Kyushu Delivery Center: Kurume-city, Fukuoka
Prefecture.
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Number of employees
350名
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SPF Animals are produced by using hysterectomy-derived
germ-free animals. The animals are housed in a barriered
animal room, and kept under stringent control
according to the standard animal production system.
Serological tests for specific pathogens are regularly
performed.
“Cr” is an abbreviation
for “Division of Cancer Treatment, National Cancer
Institute, U.S.A.” |
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| SLC produced various kind of experimental
animals according to the standard animal production
system, and kept under stringent microbiological and
genetic control. The animals are monitored regularly
to maintain health conditions and characteristics.. |
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Breeding System |
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1. Closed colony: The animals
are produced by random mating system. |
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2. Inbred strain: |
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1) Foundation stock colony: This is the “seed
stock” of the strain. Brother to sister mating
inbreeds
the pedigreed animals.
2) Multiplication colonies: The aim of these
colonies is to produce breeding stocks for final
production
of experimental animals. The breeding stock
is provided by the foundation stock
colony.
The pairing is brother to sister mating.
3) Production colonies: These colonies are only
for production of experimental animals.
Random
mating is used for animal production, rather
than brother to sister mating.
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3. Hybrid strain: Mating
between females and males of different inbred
strain produces F1 hybrids. |
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Animal Husbandry |
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Japan SLC animals are maintained
under the following conditions:
| Room temperature |
23~25℃
(except for rabbits: 20~24℃) |
| Relative humidity |
45~65% |
| Lighting
cycle |
12h light / 12h dark cycle |
| Ventilation
rate |
15 times/h,
The air-pass through the HEPA filters.
A pan-type air conditioning system is
used as a air flow system. |
Diet: Autoclaved rodent diets (Nihon Nosan Kogyo
K.K.), and autoclaved and irradiated diets (PMI
Feeds, Inc.) are available for SPF animals.
Rodent diets (Nihon Nosan Kogyo K.K.) are available
for “clean conventional” animals.
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Microbiological Monitoring |
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We routinely conduct
tests for pathogenic organisms and recto and
end parasites, and to collect serum and tissue.
The examination items are as follows:
| Examination Items |
Mice |
Rat |
Guinea pig |
Rabbits |
Hamster |
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Sendai virus |
○ |
○ |
○ |
○ |
○ |
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MHV |
○ |
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SDA |
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○ |
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Ecromelia virus |
○ |
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HFTS |
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○ |
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PVM |
○ |
○ |
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○ |
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LCM |
○ |
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MAV |
○ |
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Pseudomonas aeruginosa |
● |
● |
● |
● |
● |
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Salmonella spp. |
◎ |
◎ |
◎ |
◎ |
◎ |
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Pasteurella pneumotropica |
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● |
● |
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Pasteurella multocida |
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● |
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Bordetella bronchiseptica |
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◎ |
◎ |
◎ |
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Streptococcus pneumoniae |
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● |
● |
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Streptococcus zooepidemicus |
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● |
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Escherichia coil 0115 a, c: K(B) |
● |
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Corynebacterium kutscheri |
◎ |
◎ |
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◎ |
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Mycoplasma spp |
● |
● |
● |
● |
● |
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Tyzzer's organism |
△ |
△ |
△ |
△ |
△ |
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Syphacia spp |
□ |
□ |
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□ |
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Aspiculuris tetraptera |
□ |
□ |
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□ |
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Giardia spp |
□ |
□ |
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□ |
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Spironucleus spp |
□ |
□ |
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□ |
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Eimeria spp |
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□ |
□ |
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Psoroptes cuniculi |
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○: serological test
●: microbiological test
◎: microbiological and serological test
△: serological test, and pathologic test (if
necessary)
□: microscopic test
Selected animals in each production facility
are checked visually for possible abnormalities.
Careful management and husbandry procedures
are performed for each strain of animal. In
addition, a monitoring report on each strain
is recorded weekly to check production efficacy.
Microorganisms in the air of animal buildings
are periodically tested. The drinking water
for animals is periodically examined.
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Japan SLC animals are maintained
under the following conditions:
| Room temperature |
23~25℃ (except for rabbits:
20~24℃) |
| Relative humidity |
45~65% |
| Lighting
cycle |
12h light / 12h dark cycle |
| Ventilation
rate |
15 times/h,
The air-pass through the HEPA filters.
A pan-type air conditioning system is
used as a air flow system. |
Diet: Autoclaved rodent diets (Nihon Nosan Kogyo
K.K.), and autoclaved and irradiated diets (PMI
Feeds, Inc.) are available for SPF animals.
Rodent diets (Nihon Nosan Kogyo K.K.) are available
for “clean conventional” animals.
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Genetic Monitoring for
Inbred Strains |
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Genetic monitoring is carried out once a year
for all foundation stock strain. The test items
are as follows: Test for biochemical markers,
immunogenetic marker, micro-satellite maker.
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Standard Biological
Data |
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Studies on standard biological data are carried
out in selected stock strains as occasion arises.
Examination item in the studies are as follows.
Growth data
Organ weight data
Hematology
Clinical blood chemistry
Reproductive studies in dams and litters
Macro and Histo-pathology
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"자세한 사항은 홈페이지 www.jslc.co.jp에서 보시거나, 저희에게 연락 주시면 상세한 책자를 보내 드리겠습니다"
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