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무제 문서
 
 
 
 
 
 
      

www.jslc.co.jp


Outline of the company

Name

Japan SLC, Inc.

* Address: Japan SLC, Inc., 3371-8 Kotoh-cho, Hamamatsu, Shizuoka Prefecture 431-1103

* Tel: +81-53-486-3178/Fax: +81-53-486-3156 
 
History

1949: Establishment of Takagi Jikken Dobutsu Shiikujyo.
1967: Company was reorganized and renamed as Shizuoka Institute for Laboratory Animals, Inc.
1987: Company was renamed as Japan SLC, Inc.
1989: Sales and Delivery Division of Shizuoka Prefecture Agricultural Cooperative
Association for Animals was transferred to Japan SLC, Inc.
Capital stock

95.04 million (JPY)
Location

Headquarters-Hamamatsu, Shizuoka Prefecture.
Ohara branch-Hamamatsu, Shizuoka Prefecture.
Inasa branch- Inasa-gun, Shizuoka Prefecture.
Haruno branch-Syuchi-gun, Shizuoka Prefecture.
Nakaizu branch- Tagata-gun, Shizuoka Prefecture.
Contract Research Department and Quality Control Department
-Hamamatsu, Shizuoka Prefecture.
Tokyo Delivery Center: Machida, Tokyo.
Kyoto Delivery Center: Minami-ku, Kyoto.
Kyushu Delivery Center: Kurume-city, Fukuoka Prefecture.
Number of employees

350名
 
SPF Animals are produced by using hysterectomy-derived germ-free animals. The animals are housed in a barriered animal room, and kept under stringent control
according to the standard animal production system. Serological tests for specific pathogens are regularly performed.
“Cr” is an abbreviation for “Division of Cancer Treatment, National Cancer Institute, U.S.A.”
 
 
SLC produced various kind of experimental animals according to the standard animal production system, and kept under stringent microbiological and genetic control. The animals are monitored regularly to maintain health conditions and characteristics..
 
Breeding System
 
  1. Closed colony: The animals are produced by random mating system.
  2. Inbred strain:
 
1) Foundation stock colony: This is the “seed stock” of the strain. Brother to sister mating
inbreeds the pedigreed animals.

2) Multiplication colonies: The aim of these colonies is to produce breeding stocks for final
production of experimental animals. The breeding stock is provided by the foundation stock
colony. The pairing is brother to sister mating.

3) Production colonies: These colonies are only for production of experimental animals.
Random mating is used for animal production, rather than brother to sister mating.
  3. Hybrid strain: Mating between females and males of different inbred strain produces F1 hybrids.
 
Animal Husbandry
 
  Japan SLC animals are maintained under the following conditions:

Room temperature 23~25℃ (except for rabbits: 20~24℃)
Relative humidity 45~65%
Lighting cycle 12h light/12h dark cycle
Ventilation rate 15 times/h, The air-pass through the HEPA filters. A pan-type air conditioning system is used as a air flow system.

Diet: Autoclaved rodent diets (Nihon Nosan Kogyo K.K.), and autoclaved and irradiated diets (PMI Feeds, Inc.) are available for SPF animals. Rodent diets (Nihon Nosan Kogyo K.K.) are available for “clean conventional” animals.
미생물 모니터링
작성일 : 2011년 8월
분 류 검사 항목 검사방법 1) 검사빈도 검 사 대 상 동 물
마릿수 2) 마우스 랫 햄스터 저빌 기니픽 토끼
세 균 Pseudomonas aeruginosa 배양 2회/월 ● ● ● ● ● ●
Citrobacter rodentium 배양 2회/월 ● X X X X X
Salmonella spp. 배양 2회/월 ● ● ● ● ● ●
Salmonella typhimurium 혈청 2회/월 ● ● ● ● ● ●
Pasteurella pneumotropica 배양 2회/월 ● ● ● ● ● X
Pasteurella multocida 배양 2회/월 X X X X X ●
Bordetella bronchiseptica 4) 배양·혈청 2회/월 X ● ● ● ● ●
Streptococcus pneumoniae 배양 2회/월 X ● ● ● ● X
Streptococcus zooepidemicus 배양 2회/월 X X X X ● X
Staphylococcus aureus 5) 배양 2회/월 ● X X X X X
Corynebacterium kutscheri 배양·혈청 2회/월 ● ● ● ● X X
Clostridium piliforme 혈청 2회/월 ● ● ● ● ● ●
CAR bacillus 혈청 2회/월 ● ● X X X X
Helicobacter hepaticus PCR법 4회,
2회/년 3)		 ● ● X ● X X
Helicobacter bilis PCR법 4회,
2회/년 3)		 ● ● X ● X X
Myco
plasma		 Mycoplasma
pulmonis 6)		 배양·혈청 2회/월 ● ● ● ● ● ●
바이
러스		 Mouse hepatitis virus 혈청 2회/월 ● X X X X X
Sialodacryoadenitis virus 혈청 2회/월 X ● X X X X
Sendai virus 혈청 2회/월 ● ● ● ● ● ●
Hantavirus 혈청 3회/년 X ● ● X X X
Pneumonia virus of mice 혈청 1회/년 ● ● ● X X X
Mouse adenovirus 혈청 1회/년 ● ● X X X X
Lymphocytic choriomeningitis virus 혈청 3회/년 ● X ● X X X
Ectromelia virus 혈청 3회/년 ● X X X X X
Murine norovirus PCR법 1회/년 ● X X X X X
내부
기생충		 Pinworm 현미경 검사 2회/월 ● ● ● ● X X
Intestinal protozoa
 현미경 검사 2회/월 ● ● ● ● X X
Eimeria caviae
 현미경 검사 2회/월 X X X X ● X
Eimeria spp. 현미경 검사 2회/월 X X X X X ●
외부
기생충		 Ectoparasits 현미경 검사 2회/월 ● ● ● ● ● X
Psoroptes cuniculi 현미경 검사 2회/월 X X X X X ●
진 균 Pneumocystis
carinii 5)		 현미경 검사
·PCR법		 2회/월 ● X X X X X
Dermatophytes 배양 2회/월 ● ● X X X X
   
  1) 미생물모니터링 절차서는 병원체별 진단 법에 준하여 실행 합니다.
2) 미생물모니터링 동물 sampling 기준에 따릅니다.
3) 마우스는 4회/년, 랫은 2 회/년 실시합니다.
4) 기니픽과 토끼 이외는 배양 검사만 실시 합니다.
5) BALB/cSlc-nu 및 KSN/Slc를 검사 대상으로 합니다.
6) 마우스 및 랫은 배양검사와 혈청 반응 (ELISA 법으로 3개월/1회)을 실시하고
6) 그 외의 동물은 배양검사만 실시 합니다.
※ 검사성적보고 : 매월 검사 성적서를 발행하고, 배포합니다.
   
 
  Japan SLC animals are maintained under the following conditions:

Room temperature 23~25℃ (except for rabbits: 20~24℃)
Relative humidity 45~65%
Lighting cycle 12h light/12h dark cycle
Ventilation rate 15 times/h, The air-pass through the HEPA filters. A pan-type air conditioning system is used as a air flow system.

Diet: Autoclaved rodent diets (Nihon Nosan Kogyo K.K.), and autoclaved and irradiated diets (PMI Feeds, Inc.) are available for SPF animals. Rodent diets (Nihon Nosan Kogyo K.K.) are available for “clean conventional” animals.
Genetic Monitoring for Inbred Strains
 
Genetic monitoring is carried out once a year for all foundation stock strain. The test items are as follows: Test for biochemical markers, immunogenetic marker, micro-satellite maker.
 
Standard Biological Data
 


Studies on standard biological data are carried out in selected stock strains as occasion arises. Examination item in the studies are as follows.
Growth data
Organ weight data
Hematology
Clinical blood chemistry
Reproductive studies in dams and litters
Macro and Histo-pathology

 

 
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